{"id":13790,"date":"2026-07-16T17:05:22","date_gmt":"2026-07-16T08:05:22","guid":{"rendered":"https:\/\/www.factlog.kr\/?p=13790"},"modified":"2026-07-16T17:05:22","modified_gmt":"2026-07-16T08:05:22","slug":"%eb%8b%ad-%ec%a0%95%ec%9e%90%c2%b7%eb%82%9c%ec%9e%90-%eb%aa%a8%ed%83%9c-%ec%84%b8%ed%8f%ac-%ec%9c%a0%eb%8f%84%ed%95%98%eb%8a%94-%ed%95%b5%ec%8b%ac-%ec%97%b4%ec%87%a0-%ec%b0%be%ec%95%98%eb%8b%a4","status":"publish","type":"post","link":"https:\/\/www.factlog.kr\/?p=13790","title":{"rendered":"\ub2ed \uc815\uc790\u00b7\ub09c\uc790 \ubaa8\ud0dc \uc138\ud3ec \uc720\ub3c4\ud558\ub294 \ud575\uc2ec \uc5f4\uc1e0 \ucc3e\uc558\ub2e4."},"content":{"rendered":"<div>\n<p>\ub18d\ucd0c\uc9c4\ud765\uccad(\uccad\uc7a5 \uc774\uc2b9\ub3c8)\uc740 \ub2ed \uccb4\uc138\ud3ec\uc5d0\uc11c \uc6d0\uc2dc\uc0dd\uc2dd\uc138\ud3ec\uc758 \ud2b9\uc9d5\uc744 \ub098\ud0c0\ub0b4\ub294 \uc720\uc804\uc790\uac00 \uc791\ub3d9\ud558\ub3c4\ub85d \ud558\ub294 \ud575\uc2ec \uc870\uc808\uc778\uc790\ub97c \ubc1d\ud788\uace0, \uc774\ub97c \ud615\uad11\uc73c\ub85c \ud655\uc778\ud560 \uc218 \uc788\ub294 \ucd94\uc801 \uae30\uc220\uc744 \uac1c\ubc1c\ud588\ub2e4\uace0 \ubc1d\ud614\ub2e4.<\/p>\n<p>\uc6d0\uc2dc\uc0dd\uc2dd\uc138\ud3ec\ub294 \ucd08\uae30 \ubc30\uc544 \ubc1c\ub2ec \ub2e8\uacc4\uc5d0 \ub098\ud0c0\ub098\uba70, \uc131\uc7a5\ud558\uba74\uc11c \uc815\uc790\uc640 \ub09c\uc790\ub85c \ubd84\ud654\ud558\ub294 \uc138\ud3ec\uc774\ub2e4.<\/p>\n<p>\uc6d0\uc2dc\uc0dd\uc2dd\uc138\ud3ec\ub294 \uc77c\ubc18 \uccb4\uc138\ud3ec\uc640 \ub2ec\ub9ac DAZL, DDX4\uc640 \uac19\uc740 \uc0dd\uc2dd\uc138\ud3ec \uad00\ub828 \uc720\uc804\uc790\ub97c \ubc1c\ud604\ud558\ub294 \ud2b9\uc9d5\uc774 \uc788\ub2e4. \uadf8\ub7ec\ub098 \uc5b4\ub5a4 \uc804\uc0ac\uc778\uc790(\uc720\uc804\uc790\uc758 \uc791\ub3d9\uc744 \uc870\uc808\ud558\ub294 \ub2e8\ubc31\uc9c8)\uac00 \uc774\ub7ec\ud55c \uc720\uc804\uc790\ub4e4\uc758 \ubc1c\ud604\uc744 \uc870\uc808\ud558\ub294\uc9c0\ub294 \uc544\uc9c1 \uba85\ud655\ud788 \ubc1d\ud600\uc9c0\uc9c0 \uc54a\uc558\ub2e4.<\/p>\n<p>\uc5f0\uad6c\uc9c4\uc740 \uc6d0\uc2dc\uc0dd\uc2dd\uc138\ud3ec \uad00\ub828 \uc720\uc804\uc790\ub97c \uc870\uc808\ud558\ub294 \ud575\uc2ec \uc804\uc0ac\uc778\uc790\ub97c \ucc3e\uae30 \uc704\ud574 \ub300\uaddc\ubaa8 \uc720\uc804\uc790 \uc815\ubcf4\ub97c \ubd84\uc11d\ud574 \ud6c4\ubcf4 \uc804\uc0ac\uc778\uc790 10\uc885*\uc744 \uc120\ubc1c\ud588\ub2e4. \uc774\uc5b4 \uc720\uc804\uc790\uac00\uc704(CRISPR\/Cas9) \uae30\uc220\uc744 \uc774\uc6a9\ud574 \uc0dd\uc2dd\uc138\ud3ec \uad00\ub828 \uc720\uc804\uc790\uc778 DAZL\uc774 \ubc1c\ud604\ub418\uba74 \ud615\uad11\uc774 \ub098\ud0c0\ub098\ub294 \ucd94\uc801 \uc138\ud3ec\ub97c \uac1c\ubc1c\ud588\ub2e4.<\/p>\n<p>*\uc120\ubc1c \uc804\uc0ac\uc778\uc790(10\uc885): NANOG, POUV, SOX2, LIN28A, Blimp1 (PRDM1), TFAP2C, PRDM14, HNF4A, OTX2, CDX2<\/p>\n<p>\uc5f0\uad6c \uacb0\uacfc, \uc120\ubc1c\ud55c \uc804\uc0ac\uc778\uc790\ub97c \ub3c4\uc785\ud55c \uccb4\uc138\ud3ec\uc5d0\uc11c\ub294 DAZL \uc720\uc804\uc790\uac00 \ubc1c\ud604\ub418\uba74\uc11c \ud615\uad11\uc774 \ub098\ud0c0\ub0ac\ub2e4. \ub610\ud55c, \uc6d0\uc2dc\uc0dd\uc2dd\uc138\ud3ec\uc758 \ud2b9\uc9d5\uc744 \ubcf4\uc5ec\uc8fc\ub294 \uc720\uc804\uc790\uc640 \ub2e8\ubc31\uc9c8\ub3c4 \ud568\uaed8 \ud655\uc778\ub410\ub2e4. \uc774\ub97c \ud1b5\ud574 \uc5f0\uad6c\uc9c4\uc740 \uc120\ubc1c\ud55c \uc804\uc0ac\uc778\uc790\ub4e4\uc774 \uc6d0\uc2dc\uc0dd\uc2dd\uc138\ud3ec \uad00\ub828 \uc720\uc804\uc790 \ubc1c\ud604\uc744 \uc870\uc808\ud558\ub294 \ub370 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud55c\ub2e4\ub294 \uc0ac\uc2e4\uc744 \uc99d\uba85\ud588\ub2e4.<\/p>\n<p>\uc774\ubc88 \uc5f0\uad6c\ub294 \ub2ed\uc5d0\uc11c \uc6d0\uc2dc\uc0dd\uc2dd\uc138\ud3ec \uc720\ub3c4 \uacfc\uc815\uc744 \uc815\ubc00\ud558\uac8c \uc5f0\uad6c\ud560 \uc218 \uc788\ub294 \uae30\ubc18\uc744 \ub9c8\ub828\ud588\ub2e4\ub294 \uc810\uc5d0\uc11c \ud070 \uc758\ubbf8\uac00 \uc788\ub2e4. \uc55e\uc73c\ub85c \uc6d0\uc2dc\uc0dd\uc2dd\uc138\ud3ec \uc720\ub3c4 \uc6d0\ub9ac\ub97c \uba85\ud655\ud788 \uad6c\uba85\ud558\uace0, \ucc28\uc138\ub300 \uac00\uae08 \uc0dd\uba85\uacf5\ud559 \uc5f0\uad6c\ub97c \uc704\ud55c \uc5f0\uad6c \ud50c\ub7ab\ud3fc\uc73c\ub85c \uad11\ubc94\uc704\ud558\uac8c \ud65c\uc6a9\ub420 \uac83\uc73c\ub85c \uae30\ub300\ub41c\ub2e4.<\/p>\n<p>\uc774 \uc5f0\uad6c \uc131\uacfc\ub294 \ucd95\uc0b0 \ubd84\uc57c \uad6d\uc81c\ud559\uc220\uc9c0 \uff62Animal Bioscience\uff63 \uc800\ub110*\uc5d0 \uac8c\uc7ac\ub410\uace0, \uad00\ub828 \uae30\uc220\uc740 \ud2b9\ud5c8** \ub4f1\ub85d\uc744 \uc644\ub8cc\ud588\ub2e4.<\/p>\n<p>* \ub17c\ubb38\uac8c\uc7ac: \u201926.1. (Impact factor: 2.5)<\/p>\n<p>** \ud2b9\ud5c8\ub4f1\ub85d: DAZL \ub109\uc778 \uc0dd\uc2dd\uc138\ud3ec \ubd84\ud654 \ucd94\uc801\uc6a9 \uc138\ud3ec\uc8fc \ubc0f \uc774\uc758 \uc6a9\ub3c4(10-2944659-0000)<\/p>\n<p>\ub18d\ucd0c\uc9c4\ud765\uccad \uad6d\ub9bd\ucd95\uc0b0\uacfc\ud559\uc6d0 \ub3d9\ubb3c\ubc14\uc774\uc624\uc720\uc804\uccb4\uacfc \uc774\uacbd\ud0dc \uacfc\uc7a5\uc740\u201c\uc774\ubc88 \uc5f0\uad6c\ub85c \ub2ed \uccb4\uc138\ud3ec\uc5d0\uc11c \uc6d0\uc2dc\uc0dd\uc2dd\uc138\ud3ec \uc720\ub3c4 \uacfc\uc815\uc744 \ubd84\uc790 \uc218\uc900\uc5d0\uc11c \uc5f0\uad6c\ud560 \uc218 \uc788\ub294 \uae30\ud2c0\uc744 \ub9c8\ub828\ud588\ub2e4.\u201d\ub77c\uba70 \u201c\uc720\ub3c4 \uc138\ud3ec\uac00 \uc2e4\uc81c \uc6d0\uc2dc\uc0dd\uc2dd\uc138\ud3ec\uc758 \uae30\ub2a5\uc801 \ud2b9\uc131\uc744 \uc644\ubcbd\ud788 \uac16\ucd94\uc5c8\ub294\uc9c0 \ud655\uc778\ud558\uace0, \uc6d0\uc2dc\uc0dd\uc2dd\uc138\ud3ec \uc720\ub3c4 \uae30\uc220\uc744 \uace0\ub3c4\ud654\ud558\ub294 \ud6c4\uc18d \uc5f0\uad6c\ub97c \uc774\uc5b4\uac08 \uacc4\ud68d\uc774\ub2e4.\u201d\ub77c\uace0 \ub9d0\ud588\ub2e4.<\/p>\n<div>\n<p><strong>\ucca8\ubd80\ud30c\uc77c<\/strong><\/p>\n<ul>\n<li><a href=\"https:\/\/www.factlog.kr\/wp-content\/uploads\/2026\/07\/16-3___________________________________.pdf\" rel=\"noopener\" target=\"_blank\">16-3_\ub2ed_\uc815\uc790_\ub09c\uc790\uc758_\ubaa8\ud0dc_\uc138\ud3ec_\uc720\ub3c4\ud558\ub294_\ud575\uc2ec_\uc5f4\uc1e0_\ucc3e\uc558\ub2e4(\ucd95\uc0b0\uc6d0).pdf<\/a><\/li>\n<\/ul>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\ub18d\ucd0c\uc9c4\ud765\uccad(\uccad\uc7a5 \uc774\uc2b9\ub3c8)\uc740 \ub2ed \uccb4\uc138\ud3ec\uc5d0\uc11c \uc6d0\uc2dc\uc0dd\uc2dd\uc138\ud3ec\uc758 \ud2b9\uc9d5\uc744 \ub098\ud0c0\ub0b4\ub294 \uc720\uc804\uc790\uac00 \uc791\ub3d9\ud558\ub3c4\ub85d \ud558\ub294 \ud575\uc2ec \uc870\uc808\uc778\uc790\ub97c \ubc1d\ud788\uace0, \uc774\ub97c \ud615\uad11\uc73c\ub85c \ud655\uc778\ud560 \uc218 \uc788\ub294 \ucd94\uc801 \uae30\uc220\uc744 \uac1c\ubc1c\ud588\ub2e4\uace0 \ubc1d\ud614\ub2e4. \uc6d0\uc2dc\uc0dd\uc2dd\uc138\ud3ec\ub294 \ucd08\uae30 \ubc30\uc544 \ubc1c\ub2ec \ub2e8\uacc4\uc5d0 \ub098\ud0c0\ub098\uba70, \uc131\uc7a5\ud558\uba74\uc11c \uc815\uc790\uc640 \ub09c\uc790\ub85c \ubd84\ud654\ud558\ub294 \uc138\ud3ec\uc774\ub2e4. \uc6d0\uc2dc\uc0dd\uc2dd\uc138\ud3ec\ub294 \uc77c\ubc18 \uccb4\uc138\ud3ec\uc640 \ub2ec\ub9ac DAZL, DDX4\uc640 \uac19\uc740 \uc0dd\uc2dd\uc138\ud3ec \uad00\ub828 \uc720\uc804\uc790\ub97c \ubc1c\ud604\ud558\ub294 \ud2b9\uc9d5\uc774 \uc788\ub2e4. \uadf8\ub7ec\ub098 \uc5b4\ub5a4 \uc804\uc0ac\uc778\uc790(\uc720\uc804\uc790\uc758 \uc791\ub3d9\uc744 \uc870\uc808\ud558\ub294 \ub2e8\ubc31\uc9c8)\uac00 \uc774\ub7ec\ud55c \uc720\uc804\uc790\ub4e4\uc758 \ubc1c\ud604\uc744 [&hellip;]<\/p>\n","protected":false},"author":38,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2],"tags":[26082,26077,26081,26078,23147,26079,26076,725,26080],"class_list":["post-13790","post","type-post","status-publish","format-standard","hentry","category-2","tag-crispr","tag-26077","tag-26081","tag-26078","tag-23147","tag-26079","tag-26076","tag-725","tag-26080"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.0 - 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